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Question
If prayer starts (i.e. the iqama is called) and the person feels the call of nature, what should he do?
Answer
Praise be to Allah.He should go to the restroom and tend to the call of nature even
if this means he will miss the jama'at (congregational prayer). The
evidence: Abullah Bin Arqam said, "The Messenger of Allah
(peace be upon him) said: 'If one of you needed to go to the restroom and the
salaat starts, he should start with the restroom.' "1
From the book What Should You Do in
the Following Situations... ?
1 Abu Dawood 88 and Sahih
al-Jaami' 373.
Source: IslamQA (Sheikh Muhammed Salih Al-Munajjid)